Recruitment of transcriptional effectors by Cas9 creates cis-regulatory elements and demonstrates distance-dependent transcriptional regulation

Summary: Regulation of cardiac gene expression, especially for sarcomeric genes, is crucial for heart function and is often mediated by distal regulatory elements such as enhancers and repressors. Despite their importance, the link between transcription factor recruitment to distant genomic regions...

Olles dieđut

Bibliográfalaš dieđut

Váldodahkkit:	Jubran Boulos, Arkadiy K. Golov, Nadav Keren, Itai Erlich, Nardeen Shehadeh, Nili Avidan, Hagai Kariti, Omer Sadeh, Lilac Haimovich-Caspi, Adam Helms, Noam Kaplan, Izhak Kehat
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Elsevier 2026-01-01
Ráidu:	iScience
Fáttát:	gene network molecular mechanism of gene regulation genomic analysis
Liŋkkat:	http://www.sciencedirect.com/science/article/pii/S2589004225023016
Fáddágilkorat:	Lasit fáddágilkoriid Eai fáddágilkorat, Lasit vuosttaš fáddágilkora!