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REliable PIcking by Consensus (REPIC): a consensus methodology for harnessing multiple cryo-EM particle pickers

Abstract Cryo-EM particle identification from micrographs (“picking”) is challenging due to the low signal-to-noise ratio and lack of ground truth for particle locations. State-of-the-art computational algorithms (“pickers”) identify different particle sets, complicating the selection of the best-su...

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Autors principals: Christopher J. F. Cameron, Sebastian J. H. Seager, Fred J. Sigworth, Hemant D. Tagare, Mark B. Gerstein
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2024-10-01
Col·lecció:Communications Biology
Accés en línia:https://doi.org/10.1038/s42003-024-07045-0
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