Cryo-EM structure of a type VI secretion system-delivered membrane-depolarizing toxin involved in bacterial antagonism

Summary: Many Gram-negative bacteria use type VI secretion systems (T6SSs) to deliver toxic effector proteins into neighboring cells. Proteins in the VasX toxin family form ion-permeable channels in the bacterial cytoplasmic membrane that dissipate the proton motive force, thereby interfering with e...

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Bibliographic Details

Main Authors:	Jake Colautti, Dmitry Shatskiy, Eileen M. Bates, Nathan P. Bullen, Alexander Belyy, John C. Whitney
Format:	Artigo
Language:	Inglês
Published:	Elsevier 2025-09-01
Series:	Cell Reports
Subjects:	CP: Microbiology CP: Molecular biology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124725010344
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