Diminished expression of h2-calponin in prostate cancer cells promotes cell proliferation, migration and the dependence of cell adhesion on substrate stiffness

Calponin is an actin filament-associated protein and its h2 isoform inhibits cell motility. Here we report significant expression of h2-calponin in prostate epithelial cells, which is diminished in cancerous cells. Comparison between a prostate cancer cell line PC3 and its metastatic derivative PC3-...

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Detalles Bibliográficos

Principais autores:	M. Moazzem Hossain, Xin Wang, Raymond C. Bergan, J.-P. Jin
Formato:	Artigo
Idioma:	Inglês
Publicado:	Wiley 2014-01-01
Series:	FEBS Open Bio
Assuntos:	H2-calponin Cytoskeleton Cell motility Mechanical regulation Substrate stiffness
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S2211546314000588
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