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The role of p53 in anti-tumor immunity and response to immunotherapy

p53 is a transcription factor that regulates the expression of genes involved in tumor suppression. p53 mutations mediate tumorigenesis and occur in approximately 50% of human cancers. p53 regulates hundreds of target genes that induce various cell fates including apoptosis, cell cycle arrest, and D...

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Hlavní autoři: Lindsey Carlsen, Shengliang Zhang, Xiaobing Tian, Arielle De La Cruz, Andrew George, Taylor E. Arnoff, Wafik S. El-Deiry
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2023-08-01
Edice:Frontiers in Molecular Biosciences
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1148389/full
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