Protective activity of Streptococcus pneumoniae Spr1875 protein fragments identified using a phage displayed genomic library.

There is considerable interest in pneumococcal protein antigens capable of inducing serotype-independent immunoprotection and of improving, thereby, existing vaccines. We report here on the immunogenic properties of a novel surface antigen encoded by ORF spr1875 in the R6 strain genome. An antigenic...

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Principais autores:	Angela Cardaci, Salvatore Papasergi, Angelina Midiri, Giuseppe Mancuso, Maria Domina, Veronica Lanza Cariccio, Francesca Mandanici, Roberta Galbo, Carla Lo Passo, Ida Pernice, Paolo Donato, Susanna Ricci, Carmelo Biondo, Giuseppe Teti, Franco Felici, Concetta Beninati
Format:	Artigo
Jezik:	Inglês
Izdano:	Public Library of Science (PLoS) 2012-01-01
Serija:	PLoS ONE
Online dostop:	http://europepmc.org/articles/PMC3343019?pdf=render
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