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Promoter activity of Merkel cell Polyomavirus variants in human dermal fibroblasts and a Merkel cell carcinoma cell line

Abstract Background Merkel cell polyomavirus (MCPyV) is a human polyomavirus that establishes a life-long harmless infection in most individuals, with dermal fibroblasts believed to be the natural host cell. However, this virus is the major cause of Merkel cell carcinoma (MCC), an aggressive skin ca...

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Auteurs principaux: Ibrahim Abdulsalam, Kashif Rasheed, Baldur Sveinbjørnsson, Bernhard Ehlers, Ugo Moens
Format: Artigo
Langue:Inglês
Publié: BMC 2020-04-01
Collection:Virology Journal
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Accès en ligne:http://link.springer.com/article/10.1186/s12985-020-01317-x
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