Elevated Kallikrein-binding protein in diabetes impairs wound healing through inducing macrophage M1 polarization

Abstract Background The accumulation of M1-polarized macrophages and excessive inflammation are important in the pathogenesis of diabetic foot ulcer (DFU). However, the underlying mechanism of DFU pathogenesis and the crucial regulators of DFU are less well known. Our previous study reported that ka...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Juan Feng, Chang Dong, Yanlan Long, Lifang Mai, Meng Ren, Lingyi Li, Ti Zhou, Zhonghan Yang, Jianxing Ma, Li Yan, Xia Yang, Guoquan Gao, Weiwei Qi
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2019-06-01
Schriftenreihe:	Cell Communication and Signaling
Schlagworte:	Diabetic wound healing Kallikrein-binding protein Monocyte-macrophages Notch/NF-κB signalling
Online-Zugang:	http://link.springer.com/article/10.1186/s12964-019-0376-9
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!