Aligned electrospun poly(l-lactide) nanofibers facilitate wound healing by inhibiting macrophage M1 polarization via the JAK-STAT and NF-κB pathways

Abstract Delayed wound healing remains a challenge, and macrophages play an important role in the inflammatory process of wound healing. Morphological changes in macrophages can affect their phenotype, but little is known about the underlying mechanism. Aligned electrospun nanofibers have natural ad...

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Autori principali:	Jian Xie, Xiaowei Wu, Shang Zheng, Kaili Lin, Jiansheng Su
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2022-07-01
Serie:	Journal of Nanobiotechnology
Soggetti:	Aligned nanofibers Macrophage polarization Inflammation Wound healing JAK-STAT NF-κB
Accesso online:	https://doi.org/10.1186/s12951-022-01549-9
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