A compilation of 13 patients with metastatic colorectal cancer and concomitant BRAF and RAS family mutations

IntroductionMetastatic colorectal cancer (mCRC) exhibits significant heterogeneity in molecular profiles, influencing treatment response and patient outcomes. Mutations in v-raf murine sarcoma viral oncogene homolog B1 (BRAF) and rat sarcoma (RAS) family genes are commonly observed in mCRC. Though o...

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Autors principals:	Jigisha Srivastav, Morgan E. Lehman, Joni K. Evans, Ravi Paluri, Caio Max Sao Pedro Rocha Lima
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2025-08-01
Col·lecció:	Frontiers in Oncology
Matèries:	colorectal cancer BRAF mutation KRAS mutation NRAS mutation RAS family mutation concurrent RAS/BRAF variants
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1621412/full
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