A compilation of 13 patients with metastatic colorectal cancer and concomitant BRAF and RAS family mutations

IntroductionMetastatic colorectal cancer (mCRC) exhibits significant heterogeneity in molecular profiles, influencing treatment response and patient outcomes. Mutations in v-raf murine sarcoma viral oncogene homolog B1 (BRAF) and rat sarcoma (RAS) family genes are commonly observed in mCRC. Though o...

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Principais autores:	Jigisha Srivastav, Morgan E. Lehman, Joni K. Evans, Ravi Paluri, Caio Max Sao Pedro Rocha Lima
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2025-08-01
Serija:	Frontiers in Oncology
Teme:	colorectal cancer BRAF mutation KRAS mutation NRAS mutation RAS family mutation concurrent RAS/BRAF variants
Online dostop:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1621412/full
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