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Antigenic peptide delivery to antigen-presenting cells using a CD40-coiled coil affinity-based platform

Delivery of antigenic peptides to antigen presenting cells (APCs) such as dendritic cells (DCs) using monoclonal antibodies (mAbs) is an attractive approach to evoke antigen-specific T cell activation and improve drug efficacy. Peptide linkage to mAbs has previously been achieved through genetic fus...

Ful tanımlama

Kaydedildi:
Asıl Yazarlar: Barnabas Nyesiga, Karin Hägerbrand, Laura Varas, Anette Gjörloff Wingren, Mats Ohlin, Peter Ellmark, Laura von Schantz
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis Group 2025-12-01
Seri Bilgileri:Drug Delivery
Konular:
CD40
coiled coil
antigen presenting cells
dendritic cells
targeted delivery
Online Erişim:https://www.tandfonline.com/doi/10.1080/10717544.2025.2486340
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