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Disruption of the MreB Elongasome Is Overcome by Mutations in the Tricarboxylic Acid Cycle

The bacterial actin homolog, MreB, is highly conserved among rod-shaped bacteria and essential for growth under normal growth conditions. MreB directs the localization of cell wall synthesis and loss of MreB results in round cells and death. Using the MreB depolymerizing drug, A22, we show that chan...

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主要な著者: Brody Barton, Addison Grinnell, Randy M. Morgenstein
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2021-04-01
シリーズ:Frontiers in Microbiology
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オンライン・アクセス:https://www.frontiersin.org/articles/10.3389/fmicb.2021.664281/full
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