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Disruption of the MreB Elongasome Is Overcome by Mutations in the Tricarboxylic Acid Cycle

The bacterial actin homolog, MreB, is highly conserved among rod-shaped bacteria and essential for growth under normal growth conditions. MreB directs the localization of cell wall synthesis and loss of MreB results in round cells and death. Using the MreB depolymerizing drug, A22, we show that chan...

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Autori principali: Brody Barton, Addison Grinnell, Randy M. Morgenstein
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021-04-01
Serie:Frontiers in Microbiology
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Accesso online:https://www.frontiersin.org/articles/10.3389/fmicb.2021.664281/full
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