Lipid changes due to fenofibrate treatment are not associated with changes in DNA methylation patterns in the GOLDN study

Fenofibrate lowers triglycerides (TG) and raises high density lipoprotein cholesterol (HDLc) in dyslipidemic individuals. Several studies have shown genetic variability in lipid responses to fenofibrate treatment. It is, however, not known whether epigenetic patterns are also correlated with the cha...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Mithun eDas, Ryan eIrvin, Jin eSha, Stella eAslibekyan, Bertha eHidalgo, Rodney T Perry, Degui eZhi, Hemant K Tiwari, Devin eAbsher, Jose M Ordovas, Donna K Arnett
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2015-09-01
Schriftenreihe:	Frontiers in Genetics
Schlagworte:	DNA Methylation Fenofibrate cardiovascular disease Dyslipidemia Epigenetic changes Lipid lowering drug
Online-Zugang:	http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00304/full
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