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Association of DNA Methylation at CPT1A Locus with Metabolic Syndrome in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) Study.

In this study, we conducted an epigenome-wide association study of metabolic syndrome (MetS) among 846 participants of European descent in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN). DNA was isolated from CD4+ T cells and methylation at ~470,000 cytosine-phosphate-guanine dinucleo...

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Autori principali: Mithun Das, Jin Sha, Bertha Hidalgo, Stella Aslibekyan, Anh N Do, Degui Zhi, Dianjianyi Sun, Tao Zhang, Shengxu Li, Wei Chen, Sathanur R Srinivasan, Hemant K Tiwari, Devin Absher, Jose M Ordovas, Gerald S Berenson, Donna K Arnett, Marguerite R Irvin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2016-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC4726462?pdf=render
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