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Neuronal repair after spinal cord injury by in vivo astrocyte reprogramming mediated by the overexpression of NeuroD1 and Neurogenin-2

Abstract Background As a common disabling disease, irreversible neuronal death due to spinal cord injury (SCI) is the root cause of functional impairment; however, the capacity for neuronal regeneration in the developing spinal cord tissue is limited. Therefore, there is an urgent need to investigat...

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Hoofdauteurs: Zuliyaer Talifu, Chunjia Zhang, Xin Xu, Yunzhu Pan, Han Ke, Zehui Li, Wubo Liu, Huayong Du, Xiaoxin Wang, Feng Gao, Degang Yang, Yingli Jing, Yan Yu, Liangjie Du, Jianjun Li
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMC 2024-08-01
Reeks:Biological Research
Onderwerpen:
Spinal cord injury
Astrocytes
Reprogramming
Nerve regeneration
Nerve repair
Online toegang:https://doi.org/10.1186/s40659-024-00534-w
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