Inhibition of phospholipase D promotes neurological function recovery and reduces neuroinflammation after spinal cord injury in mice

IntroductionSpinal cord injury (SCI) is a severely disabling disease. Hyperactivation of neuroinflammation is one of the main pathophysiological features of secondary SCI, with phospholipid metabolism playing an important role in regulating inflammation. Phospholipase D (PLD), a critical lipid-signa...

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Detalhes bibliográficos

Principais autores:	Han Ke, Fan Bai, Zihan Li, Yanbing Zhu, Chunjia Zhang, Yan Li, Zuliyaer Talifu, Yunzhu Pan, Wubo Liu, Xin Xu, Feng Gao, Degang Yang, Liangjie Du, Yan Yu, Jianjun Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2024-03-01
coleção:	Frontiers in Cellular Neuroscience
Assuntos:	spinal cord injury phospholipase D neuroinflammation transcriptome sequencing analysis protein microarray analysis
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fncel.2024.1352630/full
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