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Current challenges and emerging opportunities of chimeric antigen receptor-engineered cell immunotherapy

Abstract Chimeric antigen receptor (CAR) engineered cellular immunotherapy offers the potential for precise targeting and elimination of tumor cells, providing a tailored approach to cancer treatment. CAR-T cells demonstrate significant anti-tumor activity among these therapies. Nonetheless, these t...

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Principais autores: Yong Liu, Yifei Duan, Zefan Du, Bo Lu, Su Liu, Lindi Li, Mengyao Tian, Liang Li, Ran Yao, Cheng Ouyang, Mo Yang, Chun Chen
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-07-01
Serier:Experimental Hematology & Oncology
Fag:
CAR-T
CAR-NK
CAR-M
Immunotherapy
Clinical application
Online adgang:https://doi.org/10.1186/s40164-025-00683-y
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