Some old 2-(4-(Aryl)- thiazole-2-yl)-3a,4,7,7a-tetrahydro-1H-4,7-tethanoisoindole-1,3(2H)-dione derivatives: Synthesis, inhibition effects and molecular docking studies on Aldose reductase and α-Glycosidase

Utilizing the simple chromatic techniques, Aldose reductase (AR) was derived from sheep liver. In addition, α-glycosidase from Saccharomyces cerevisiae was used as the enzyme. It was determined the interactions between compounds and the enzymes. Molecular docking method used to compare biological ac...

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Hlavní autoři:	Burak Tüzün, Mustafa Ceylan, Parham Taslımı, Yeliz Demir, Hatice Esra Duran, Ümit Muhammet Koçyiğit, Osman Nuri Aslan, İlhami Gülçin
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Sivas Cumhuriyet Üniversitesi 2021-09-01
Edice:	Cumhuriyet Science Journal
Témata:	asimetrik sentez kiral organik katalizörler enzim inhibisyonu aldoz redüktaz α-glikosidaz moleküler yerleştirme asymmetric synthesis enzyme inhibition aldose reductase α-glycosidase molecular docking
On-line přístup:	https://dergipark.org.tr/en/download/article-file/1641824
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