Some old 2-(4-(Aryl)- thiazole-2-yl)-3a,4,7,7a-tetrahydro-1H-4,7-tethanoisoindole-1,3(2H)-dione derivatives: Synthesis, inhibition effects and molecular docking studies on Aldose reductase and α-Glycosidase

Utilizing the simple chromatic techniques, Aldose reductase (AR) was derived from sheep liver. In addition, α-glycosidase from Saccharomyces cerevisiae was used as the enzyme. It was determined the interactions between compounds and the enzymes. Molecular docking method used to compare biological ac...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Burak Tüzün, Mustafa Ceylan, Parham Taslımı, Yeliz Demir, Hatice Esra Duran, Ümit Muhammet Koçyiğit, Osman Nuri Aslan, İlhami Gülçin
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Sivas Cumhuriyet Üniversitesi 2021-09-01
Schriftenreihe:	Cumhuriyet Science Journal
Schlagworte:	asimetrik sentez kiral organik katalizörler enzim inhibisyonu aldoz redüktaz α-glikosidaz moleküler yerleştirme asymmetric synthesis enzyme inhibition aldose reductase α-glycosidase molecular docking
Online-Zugang:	https://dergipark.org.tr/en/download/article-file/1641824
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