Leptin: a gender and obesity-related marker predictive of metabolic comorbidities and therapeutic response to anti-IL-23 biologic drugs in psoriatic patients

IntroductionPsoriasis is a chronic immune-mediated inflammatory skin disorder, frequently associated with comorbidities such as obesity, which can exacerbate its severity and hinder treatment efficacy. Psoriasis pathogenesis involves complex interactions among genetic, environmental, hormonal factor...

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Hlavní autoři:	Roberta Belli, Anna Dattolo, Francesca Sampogna, Emanuela Gubinelli, Daniela Lulli, Gaia Moretta, Emanuele Scala, Luca Sanna, Matteo Megna, Maria Vittoria Cannizzaro, Melania Parisi, Cecilia Luordi, Claudia Scarponi, Maria Quaranta, Maria Grazia Lolli, Lorena Silvestri, Paolo Gisondi, Giampiero Girolomoni, Sabatino Pallotta, Cristina Albanesi, Laura Mercurio, Stefania Madonna
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2025-07-01
Edice:	Frontiers in Immunology
Témata:	psoriasis obesity adipokines anti-IL-17 biologics anti-IL-23 biologics gender
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1607312/full
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