The Right Key, the Wrong Lock: TIGIT Checkpoint Blockade and the Road to Precision Immunotherapy

T-cell immunoreceptor with immunoglobulin and immunoreceptor tyrosine-based inhibitory motif (ITIM) domains (TIGIT) emerged as one of the most promising next-generation immune checkpoint targets following the success of programmed cell death protein 1 (PD-1), programmed death-ligand 1 (PD-L1), and c...

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Autors principals:	Shukur Wasman Smail, Hawro Taha Hamza, Mohammed Awat Ali, Raya Kh. Yashooa, Wissam Albeer Nooh, Ahmed Abdulrazzaq Bapir, Dlzar B. Rahman, Mohammed O. Rahman, Hiba A. Haseeb, Nivar B. Maaruf, Shadyar O. Majeed, Iman Ezzat, Christer Janson
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2026-08-01
Col·lecció:	Pharmaceutics
Matèries:	TIGIT CD155 CD226 immune checkpoint blockade precision immunotherapy tumor microenvironment
Accés en línia:	https://www.mdpi.com/1999-4923/18/8/970
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