Development of a potential PET probe for HDAC6 imaging in Alzheimer's disease

Although the epigenetic regulatory protein histone deacetylase 6 (HDAC6) has been recently implicated in the etiology of Alzheimer's disease (AD), little is known about the role of HDAC6 in the etiopathogenesis of AD and whether HDAC6 can be a potential therapeutic target for AD. Here, we performed...

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Principais autores:	Ping Bai, Prasenjit Mondal, Frederick A. Bagdasarian, Nisha Rani, Yan Liu, Ashley Gomm, Darcy R. Tocci, Se Hoon Choi, Hsiao-Ying Wey, Rudolph E. Tanzi, Can Zhang, Changning Wang
格式:	Artigo
語言:	Inglês
出版:	Elsevier 2022-10-01
叢編:	Acta Pharmaceutica Sinica B
主題:	HDAC6 Alzheimer's disease Radiotracer PET imaging Epigenetic
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2211383522002398
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