Silencing of PIGU inhibits the progression of esophageal squamous cell carcinoma through the PI3K/AKT signaling pathway

Abstract Phosphatidylinositol glycan anchor biosynthesis class U (PIGU), a crucial subunit of the glycosylphosphatidylinositol transamidase (GPI-T) complex, is an oncogene in hepatocellular carcinoma. However, its role in esophageal squamous cell carcinoma (ESCC) remains poorly understood. This stud...

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Autores principales:	Ji Zuo, Haiyang Guo, Guangbing Hu, Yuman HE, Yong Tang, Jie Li, Yutong Cui, Shiqi Liang, Xinrui Chen, Zichen Luo, Xiaobo Wang, Xianfei Wang
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Portfolio 2025-08-01
Colección:	Scientific Reports
Materias:	PIGU Esophageal squamous cell carcinoma PI3K/AKT Cell cycle Apoptosis
Acceso en línea:	https://doi.org/10.1038/s41598-025-08748-y
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