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Generation of gene-level resolution chromosome contact maps in bacteria and archaea

Summary: Chromosome conformation capture (Hi-C) has become a routine method for probing the 3D organization of genomes. However, when applied to bacteria and archaea, current protocols are expensive and limited in their resolution. By dissecting the different steps of published eukaryotic and prokar...

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Hlavní autoři: Charlotte Cockram, Agnès Thierry, Romain Koszul
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2021-06-01
Edice:STAR Protocols
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On-line přístup:http://www.sciencedirect.com/science/article/pii/S2666166721002197
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