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Generation of gene-level resolution chromosome contact maps in bacteria and archaea

Summary: Chromosome conformation capture (Hi-C) has become a routine method for probing the 3D organization of genomes. However, when applied to bacteria and archaea, current protocols are expensive and limited in their resolution. By dissecting the different steps of published eukaryotic and prokar...

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Autors principals: Charlotte Cockram, Agnès Thierry, Romain Koszul
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2021-06-01
Col·lecció:STAR Protocols
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Accés en línia:http://www.sciencedirect.com/science/article/pii/S2666166721002197
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