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Genotoxic Damage to Glioblastoma Cells Treated with 6 MV X-Radiation in The Presence or Absence of Methoxy Estradiol, IUDR or Topotecan

Objective: To explore the cumulative genotoxic damage to glioblastoma (GBM) cells, grown as multicellular spheroids, following exposure to 6 MV X-rays (2 Gy, 22 Gy) with or without, 2- methoxy estradiol (2ME2), iododeoxyuridine (IUDR) or topotecan (TPT), using the Picogreen assay. Materials and...

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Main Authors: Nazila Eyvazzadeh, Ali Neshasteh-Riz, Seyed Rabee Mahdavi, Afshin Mohsenifar
Format: Artigo
Language:Inglês
Published: Royan Institute (ACECR), Tehran 2015-07-01
Series:Cell Journal
Subjects:
DNA Damage
HIF-1Alpha
2-Methoxyestradiol
Topotecan
Picogreen
Online Access:http://celljournal.org/web/journal/article/380/download
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