Cracking the code of cancer immunotherapy resistance: emerging roles of pyroptosis and necroptosis

Abstract Therapeutic resistance and recurrent metastasis continue to pose major obstacles in the treatment of malignant tumors worldwide. Immunogenic cell death (ICD), characterized by its ability to both eliminate cancer cells and stimulate antitumor immune responses, has emerged as a promising str...

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Principais autores:	Kunming Lei, Jiujiu Chen, Yanrong Deng, Yige Peng, Xiang Zhai, Xianghai Ren, Jianhong Zhao, Baoxiang Chen, Congqing Jiang
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2025-11-01
Serija:	Journal of Experimental & Clinical Cancer Research
Teme:	Cancer immunotherapy resistance Immunogenic cell death Pyroptosis Necroptosis Tumor microenvironment
Online dostop:	https://doi.org/10.1186/s13046-025-03569-3
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