H-Ras nanocluster stability regulates the magnitude of MAPK signal output.

H-Ras is a binary switch that is activated by multiple co-factors and triggers several key cellular pathways one of which is MAPK. The specificity and magnitude of downstream activation is achieved by the spatio-temporal organization of the active H-Ras in the plasma membrane. Upon activation, the G...

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Үндсэн зохиолчид:	Barak Rotblat, Liron Belanis, Hong Liang, Roni Haklai, Galit Elad-Zefadia, John F Hancock, Yoel Kloog, Sarah J Plowman
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Public Library of Science (PLoS) 2010-08-01
Цуврал:	PLoS ONE
Онлайн хандалт:	http://europepmc.org/articles/PMC2916832?pdf=render
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!