Enantioselectivity in blood-cerebrospinal fluid barrier permeability of substituted p-phenylenediamine quinones in patients with leptomeningeal metastasis

Substituted p-phenylenediamine quinones (PPD-Qs), widespread environmental contaminants arising from rubber antioxidants, exhibit documented toxicity and have been detected in human biological matrices. Penetration behaviors of various PPD-Qs across the blood-cerebrospinal fluid barrier remain uncle...

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Autors principals:	Yuxiang Weng, Zebin Fang, Xiaoyi Wang, Sihan Mao, Feng Xiao, Luyuan Zhang, Weijian Fan, Chao Zhang, Ping Lan, Renya Zhan, Kaiyuan Huang, Qingsheng Xu
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2026-02-01
Col·lecció:	Ecotoxicology and Environmental Safety
Matèries:	Enantioselectivity 6PPD-Q Cerebrospinal fluid Human serum Blood-cerebrospinal fluid barrier
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S0147651326002241
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