The open architecture of HD-PTP phosphatase provides new insights into the mechanism of regulation of ESCRT function
Abstract HD-PTP is a tumour suppressor phosphatase that controls endocytosis, down-regulation of mitogenic receptors and cell migration. Central to its role is the specific recruitment of critical endosomal sorting complexes required for transport (ESCRTs). However, the molecular mechanisms that ena...
में बचाया:
| मुख्य लेखकों: | , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Nature Portfolio
2017-08-01
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| श्रृंखला: | Scientific Reports |
| ऑनलाइन पहुंच: | https://doi.org/10.1038/s41598-017-09467-9 |
| टैग: |
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