Alpha-Ketoglutarate: A Potential Inner Mitochondrial and Cytosolic Protector against Peroxynitrite and Peroxynitrite-Induced Nitration?

The generation of peroxynitrite (ONOO⁻) is associated with several diseases, including atherosclerosis, hypertension, neurodegeneration, cancer, inflammation, and sepsis. Alpha-ketoglutarate (αKG) is a known potential highly antioxidative agent for radical oxidative species such as peroxi...

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Detalhes bibliográficos

Principais autores:	Joachim Greilberger, Michaela Greilberger, Reinhold Wintersteiger, Klaus Zangger, Ralf Herwig
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-09-01
coleção:	Antioxidants
Assuntos:	alpha-ketoglutarate (αKG) peroxynitrite (ONOO<sup>−</sup>) reactive oxygen and nitrogen species (RONS)
Acesso em linha:	https://www.mdpi.com/2076-3921/10/9/1501
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