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Potential Ameliorating Role of Spironolactone in Trastuzumab-induced Cardiotoxicity: A Narrative Review

Background: Around 20% of breast cancers (BCs) overexpress Human Epidermal Growth Factor Receptor 2 (HER-2). HER-2 overexpression is associated with increased tumor aggressiveness and poor prognosis. Trastuzumab (an anti-HER2 monoclonal antibody) has been reported to improve overall survival in earl...

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Hauptverfasser: Amir Ghabousian, Azin Alizadehasl, Niloufar Ansari, Mehrdad Haghazali
Format: Artigo
Sprache:Inglês
Veröffentlicht: Shaheed Beheshti University of Medical Sciences 2021-11-01
Schriftenreihe:International Journal of Medical Toxicology and Forensic Medicine
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Online-Zugang:https://journals.sbmu.ac.ir/ijmtfm/article/view/36127
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