Host factor Rab4b mediates internalization and intoxication of 3D4/21 cells by the active subunit of the Glaesserella parasuis cytolethal distending toxin via influencing EEA1 expression

BackgroundThe cytolethal distending toxin (CDT), a significant exotoxin, is closely linked to the pathogenicity of Glaesserella parasuis (GPS), but its pathogenic not yet fully elucidated. Previously, we identified Rab4b as a potential host factor contributing to the cytotoxicity of GpCDT through a...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Yiwen Zhang, Zhen Yang, Senyan Du, Qin Zhao, Xiaobo Huang, Rui Wu, Yiping Wang, Qigui Yan, Sanjie Cao, Yiping Wen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2025-10-01
Edice:	Frontiers in Microbiology
Témata:	Glaesserella parasuis Rab4b GpCDT EEA1 vesicle trafficking
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fmicb.2025.1660176/full
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!