Pachymic acid alleviates metabolic dysfunction-associated steatotic liver disease by inhibiting ferroptosis through PPARα

IntroductionMetabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by excessive lipid deposition in hepatocytes without a history of significant alcohol consumption. Pachymic acid (Pac), a bioactive triterpenoid from Poria cocos, has shown promise in treating MASLD due to...

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المؤلفون الرئيسيون:	Guilin Ren, Yiyou Lin, Jiannan Qiu, Congcong Zhang, Lin Chen, Linwensi Zhu, Xiaohui Fan, Xiaobing Dou, Qingsheng Liu
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Frontiers Media S.A. 2025-05-01
سلاسل:	Frontiers in Pharmacology
الموضوعات:	pachymic acid metabolic dysfunction-associated steatotic liver disease ferroptosis PPARα MAPKs signaling pathway
الوصول للمادة أونلاين:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1554850/full
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!