Addressing RNA integrity to determine the impact of mitochondrial DNA mutations on brain mitochondrial function with age.
Mitochondrial DNA (mtDNA) mutations can result in mitochondrial dysfunction, but emerging experimental data question the fundamental role of mtDNA mutagenesis in age-associated mitochondrial impairment. The multicopy nature of mtDNA renders the impact of a given mtDNA mutation unpredictable. In this...
Gardado en:
| Principais autores: | , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science (PLoS)
2014-01-01
|
| Series: | PLoS ONE |
| Acceso en liña: | http://europepmc.org/articles/PMC4018447?pdf=render |
| Tags: |
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|