RIG-I self-oligomerization is either dispensable or very transient for signal transduction.
Effective host defence against viruses depends on the rapid triggering of innate immunity through the induction of a type I interferon (IFN) response. To this end, microbe-associated molecular patterns are detected by dedicated receptors. Among them, the RIG-I-like receptors RIG-I and MDA5 activate...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Acceso en liña: | http://europepmc.org/articles/PMC4178188?pdf=render |
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