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Limited threat of Plasmodium falciparum pfhrp2 and pfhrp3 gene deletion to the utility of HRP2-based malaria RDTs in Northern Uganda

Abstract Background Rapid diagnostic tests (RDTs) that detect Plasmodium falciparum histidine-rich protein-2 (PfHRP2) are exclusively deployed in Uganda, but deletion of the pfhrp2/3 target gene threatens their usefulness as malaria diagnosis and surveillance tools. Methods A cross-sectional survey...

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Hlavní autoři: Bosco B. Agaba, David Smith, Jye Travis, Cielo Pasay, Monica Nabatanzi, Emmanuel Arinaitwe, Isaac Ssewanyana, Susan Nabadda, Jane Cunningham, Moses R. Kamya, Qin Cheng
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2024-01-01
Edice:Malaria Journal
Témata:
Malaria
Rapid diagnostic tests
Plasmodium falciparum
Histidine rich protein
pfhrp2 and pfhrp3 Gene deletion
On-line přístup:https://doi.org/10.1186/s12936-023-04830-w
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