Limited threat of Plasmodium falciparum pfhrp2 and pfhrp3 gene deletion to the utility of HRP2-based malaria RDTs in Northern Uganda

Abstract Background Rapid diagnostic tests (RDTs) that detect Plasmodium falciparum histidine-rich protein-2 (PfHRP2) are exclusively deployed in Uganda, but deletion of the pfhrp2/3 target gene threatens their usefulness as malaria diagnosis and surveillance tools. Methods A cross-sectional survey...

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Bibliografski detalji

Glavni autori:	Bosco B. Agaba, David Smith, Jye Travis, Cielo Pasay, Monica Nabatanzi, Emmanuel Arinaitwe, Isaac Ssewanyana, Susan Nabadda, Jane Cunningham, Moses R. Kamya, Qin Cheng
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2024-01-01
Serija:	Malaria Journal
Teme:	Malaria Rapid diagnostic tests Plasmodium falciparum Histidine rich protein pfhrp2 and pfhrp3 Gene deletion
Online pristup:	https://doi.org/10.1186/s12936-023-04830-w
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