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CYP2E1 plays a suppressive role in hepatocellular carcinoma by regulating Wnt/Dvl2/β-catenin signaling

Abstract Objective Knowledge of the role of CYP2E1 in hepatocarcinogenesis is largely based on epidemiological and animal studies, with a primary focus on the role of CYP2E1 in metabolic activation of procarcinogens. Few studies have directly assessed the effects of CYP2E1 on HCC malignant phenotype...

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Príomhchruthaitheoirí: Lili Zhu, Xiaobei Yang, Jingyu Feng, Jian Mao, Qidong Zhang, Mengru He, Yang Mi, Yingwu Mei, Ge Jin, Haifeng Zhang
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: BMC 2022-05-01
Sraith:Journal of Translational Medicine
Ábhair:
Rochtain ar líne:https://doi.org/10.1186/s12967-022-03396-6
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