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Extreme-Depth Re-sequencing of Mitochondrial DNA Finds No Evidence of Paternal Transmission in Humans.

Recent reports have questioned the accepted dogma that mammalian mitochondrial DNA (mtDNA) is strictly maternally inherited. In humans, the argument hinges on detecting a signature of inter-molecular recombination in mtDNA sequences sampled at the population level, inferring a paternal source for th...

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Autors principals: Angela Pyle, Gavin Hudson, Ian J Wilson, Jonathan Coxhead, Tania Smertenko, Mary Herbert, Mauro Santibanez-Koref, Patrick F Chinnery
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2015-05-01
Col·lecció:PLoS Genetics
Accés en línia:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1005040&type=printable
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