Unbalanced production of LTB4/PGE2 driven by diabetes increases susceptibility to cutaneous leishmaniasis

Poorly controlled diabetes mellitus leads to several comorbidities, including susceptibility to infections. Hyperglycemia increases phagocyte responsiveness, however immune cells from people with diabetes show inadequate antimicrobial functions. We and others have shown that aberrant production of l...

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Hlavní autoři:	Icaro Bonyek-Silva, Sara Nunes, Reinan L. Santos, Filipe R. Lima, Alexsandro Lago, Juliana Silva, Lucas P. Carvalho, Sergio M. Arruda, Henrique C. Serezani, Edgar M. Carvalho, Claudia I. Brodskyn, Natalia M. Tavares
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis Group 2020-01-01
Edice:	Emerging Microbes and Infections
Témata:	Diabetes human leishmaniasis Leishmania braziliensis lipid mediators LTB4 PGE2
On-line přístup:	https://www.tandfonline.com/doi/10.1080/22221751.2020.1773744
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