Unbalanced production of LTB4/PGE2 driven by diabetes increases susceptibility to cutaneous leishmaniasis

Poorly controlled diabetes mellitus leads to several comorbidities, including susceptibility to infections. Hyperglycemia increases phagocyte responsiveness, however immune cells from people with diabetes show inadequate antimicrobial functions. We and others have shown that aberrant production of l...

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Principais autores:	Icaro Bonyek-Silva, Sara Nunes, Reinan L. Santos, Filipe R. Lima, Alexsandro Lago, Juliana Silva, Lucas P. Carvalho, Sergio M. Arruda, Henrique C. Serezani, Edgar M. Carvalho, Claudia I. Brodskyn, Natalia M. Tavares
Format:	Artigo
Jezik:	Inglês
Izdano:	Taylor & Francis Group 2020-01-01
Serija:	Emerging Microbes and Infections
Teme:	Diabetes human leishmaniasis Leishmania braziliensis lipid mediators LTB4 PGE2
Online dostop:	https://www.tandfonline.com/doi/10.1080/22221751.2020.1773744
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