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Identification of CD8+ T-cell exhaustion signatures for prognosis in HBV-related hepatocellular carcinoma patients by integrated analysis of single-cell and bulk RNA-sequencing

Abstract Background HBV infection is the leading risk factor for HCC. HBV infection has been confirmed to be associated with the exhaustion status of CD8+ T cells and immunotherapeutic efficacy in HCC. In this study, we aimed to investigate the prognostic value of the CD8+ T-cell exhaustion signatur...

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Bibliografske podrobnosti
Principais autores: Jianhao Li, Han Chen, Lang Bai, Hong Tang
Format: Artigo
Jezik:Inglês
Izdano: BMC 2024-01-01
Serija:BMC Cancer
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Online dostop:https://doi.org/10.1186/s12885-023-11804-3
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