Metabolic and Stress Response Changes Precede Disease Onset in the Spinal Cord of Mutant SOD1 ALS Mice

Many Amyotrophic Lateral Sclerosis (ALS) patients experience hypermetabolism, or an increase in measured vs. calculated metabolic rate. The cause of hypermetabolism and the effects on neuronal metabolism in ALS are currently unknown, but the efficacy of dietary interventions shows promise for metabo...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Gavin Pharaoh, Kavithalakshmi Sataranatarajan, Kaitlyn Street, Shauna Hill, Jake Gregston, Bumsoo Ahn, Caroline Kinter, Michael Kinter, Holly Van Remmen
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Frontiers Media S.A. 2019-05-01
Sarja:	Frontiers in Neuroscience
Aiheet:	amyotrophic lateral sclerosis (ALS) SOD1G93A ALS mouse model metabolism hypermetabolism mitochondria antioxidants
Linkit:	https://www.frontiersin.org/article/10.3389/fnins.2019.00487/full
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