Bicistronic CAR-T cells targeting CD123 and CLL1 for AML to reduce the risk of antigen escape
Purpose: Acute myeloid leukemia (AML) is a highly heterogeneous neoplastic disease with a poor prognosis that relapses even after its treatment with chimeric antigen receptor (CAR)-T cells targeting a single antigen. CD123 and CLL1 are expressed in most AML blasts and leukemia stem cells, and their...
Tallennettuna:
| Päätekijät: | , , , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Elsevier
2023-08-01
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| Sarja: | Translational Oncology |
| Aiheet: | |
| Linkit: | http://www.sciencedirect.com/science/article/pii/S1936523323000815 |
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