SomaLogic proteomics reveals new biomarkers and provides mechanistic, clinical insights into Acetyl coA Carboxylase (ACC) inhibition in Non-alcoholic Steatohepatitis (NASH)

Abstract Non-alcoholic Fatty Liver Disease (NAFLD) and Non-alcoholic Steatohepatitis (NASH) are major metabolic diseases with increasing global prevalence and no approved therapies. There is a mounting need to develop biomarkers of diagnosis, prognosis and treatment response that can effectively rep...

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Hlavní autoři:	Pitchumani Sivakumar, Michelle Saul, Douglas Robinson, Lindsay E. King, Neeta B. Amin
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2024-07-01
Edice:	Scientific Reports
Témata:	NAFLD/NASH Biomarkers Acetyl CoA Carboxylase Liver fibrosis SomaLogic proteomics
On-line přístup:	https://doi.org/10.1038/s41598-024-67843-8
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