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Gasdermins: New Therapeutic Targets in Host Defense, Inflammatory Diseases, and Cancer

Gasdermins (GSDMs) are a class of pore-forming proteins related to pyroptosis, a programmed cell death pathway that is induced by a range of inflammatory stimuli. Small-scale GSDM activation and pore formation allow the passive release of cytokines, such as IL-1β and IL-18, and alarmins, but, whenev...

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Váldodahkkit: Laura Magnani, Mariasilvia Colantuoni, Alessandra Mortellaro
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Frontiers Media S.A. 2022-07-01
Ráidu:Frontiers in Immunology
Fáttát:
Liŋkkat:https://www.frontiersin.org/articles/10.3389/fimmu.2022.898298/full
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