Gasdermins: New Therapeutic Targets in Host Defense, Inflammatory Diseases, and Cancer
Gasdermins (GSDMs) are a class of pore-forming proteins related to pyroptosis, a programmed cell death pathway that is induced by a range of inflammatory stimuli. Small-scale GSDM activation and pore formation allow the passive release of cytokines, such as IL-1β and IL-18, and alarmins, but, whenev...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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Frontiers Media S.A.
2022-07-01
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| Schriftenreihe: | Frontiers in Immunology |
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| Online-Zugang: | https://www.frontiersin.org/articles/10.3389/fimmu.2022.898298/full |
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